Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety, depression, and substances use disorders, among others. Alcohol is a widely used substance in the world and its acute effects on a behavioral level are known. The effect of environmental stress and...
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Universidad Antonio Nariño
2021
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| _version_ | 1812646806054502400 |
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| author | Franco Restrepo, Juan Esteban |
| author2 | Vargas Vargas, Rafael Antonio |
| author_facet | Vargas Vargas, Rafael Antonio Franco Restrepo, Juan Esteban |
| author_sort | Franco Restrepo, Juan Esteban |
| collection | DSpace |
| description | Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety,
depression, and substances use disorders, among others. Alcohol is a widely used substance in the
world and its acute effects on a behavioral level are known. The effect of environmental stress and
substances on behavior has been studied separately. Short and long-term stress in zebrafish can
generate alterations in the CNS affecting anxiety levels in different behavioral tests such as
locomotion, social, learning and memory behavior. However, in the brain, the molecular effects of
environmental stress are poorly understood in association with alcohol and other substances such
as caffeine, consumed throughout the world. |
| format | Tesis y disertaciones (Maestría y/o Doctorado) |
| id | repositorio.uan.edu.co-123456789-5090 |
| institution | Repositorio Digital UAN |
| language | spa |
| publishDate | 2021 |
| publisher | Universidad Antonio Nariño |
| record_format | dspace |
| spelling | repositorio.uan.edu.co-123456789-50902024-10-09T22:34:44Z Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra Franco Restrepo, Juan Esteban Vargas Vargas, Rafael Antonio Forero Garzón, Diego Alexander Pez Cebra Cafeina Etanol Estrés Zebra fish Caffein Ethanol Stress Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety, depression, and substances use disorders, among others. Alcohol is a widely used substance in the world and its acute effects on a behavioral level are known. The effect of environmental stress and substances on behavior has been studied separately. Short and long-term stress in zebrafish can generate alterations in the CNS affecting anxiety levels in different behavioral tests such as locomotion, social, learning and memory behavior. However, in the brain, the molecular effects of environmental stress are poorly understood in association with alcohol and other substances such as caffeine, consumed throughout the world. El estrés es un factor de riesgo para diversas enfermedades orgánicas incluyendo trastornos psiquiátricos como la ansiedad, depresión, consumo de sustancias adictivas entre otros. El alcohol es una sustancia ampliamente usada en el mundo y sus efectos agudos a nivel comportamental son conocidos. El efecto del estrés ambiental y sustancias sobre el comportamiento se ha estudiado por separado. El estrés a corto y largo plazo en el pez cebra puede generar alteraciones en el SNC afectando los niveles de ansiedad en diferentes pruebas del comportamiento tales como la conducta motora, social, aprendizaje y memoria. Sin embargo, a nivel molecular en el cerebro son poco conocidos los efectos del estrés ambiental en conjunto con el alcohol y otras sustancias como la cafeína, consumidas en todo el mundo. Doctor(a) en Ciencias de la salud Doctorado Presencial Proyecto 2021-10-26T21:25:48Z 2021-10-26T21:25:48Z 2021-06-28 Tesis y disertaciones (Maestría y/o Doctorado) info:eu-repo/semantics/acceptedVersion http://purl.org/coar/resource_type/c_db06 http://purl.org/coar/version/c_970fb48d4fbd8a85 Tesis/Trabajo de grado - Monografía - Doctorado http://repositorio.uan.edu.co/handle/123456789/5090 Abreu, M., Koakoski, G., Ferreira, D., Oliveira, T., Rosa, J., & Gusso, D. et al. (2014). Diazepam and Fluoxetine Decrease the Stress Response in Zebrafish. Plos ONE, 9(7), e103232. doi: 10.1371/journal.pone.0103232 Alazizi, A., Liu, M., Williams, F., Kurogi, K., Sakakibara, Y., Suiko, M., & Liu, M. (2011). Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish. Aquatic Toxicology, 102(1-2), 18-23. doi: 10.1016/j.aquatox.2010.12.016 Asakawa, K., Suster, M. L., Mizusawa, K., Nagayoshi, S., Kotani, T., Urasaki, A.,Kishimoto, Y., Hibi, M. and Kawakami, K. (2008). Genetic dissection of neuralcircuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish.Proc. Natl. Acad. Sci. USA 105, 1255-1260. Barreto-Valer, K., López-Bellido, R., Macho Sánchez-Simón, F., & Rodríguez, R. (2012). Modulation by Cocaine of Dopamine Receptors through miRNA-133b in Zebrafish Embryos. Plos ONE, 7(12), e52701. doi: 10.1371/journal.pone.0052701 Cachat J, Canavello P, Elegante M, Bartels B, Hart P, Bergner C, et al. Modeling withdrawal syndrome in zebrafish. Behav Brain Res. 208.2 (2010), pp. 371-376. https://doi.org/10.1016/j.bbr.2009.12.004 Castaño, G., Sierra, G., Sánchez, D., Torres, Y., Salas, C., & Buitrago, C. (2017). Trastornos mentales y consumo de drogas en la población víctima del conflicto armado en tres ciudades de Colombia. Biomédica, 38, 77–92.doi:10.7705/biomedica.v38i0.3890 Daré, L., Bruand, P., Gérard, D., Marin, B., Lameyre, V., Boumédiène, F., & Preux, P. (2019). Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis. BMC Public Health, 19(1). doi: 10.1186/s12889-019-6623-6 Echevarria DJ, Hammack CM, Jouandot DJ, Toms CN. Does Acute Alcohol Exposure Modulate Aggressive Behaviors in the Zebrafish (Danio rerio), or is the Bark Worse than the Bite? Int J Comp Psychol. 23 (2010). https://escholarship.org/uc/item/2px3t3jc Eddins, D., Petro, A., Williams, P., Cerutti, D., & Levin, E. (2008). Nicotine effects on learning in zebrafish: the role of dopaminergic systems. Psychopharmacology, 202(1-3), 103-109. doi: 10.1007/s00213-008-1287-4 Emerson, A. J., Kappenman, D. P., Ronan, P. J., Renner, K. J., and Summers, C. H. (2000). Stress induces rapid changes in serotonergic activity: restraint and exertion. Behav. Brain Res. 111, 83–92. doi: 10.1016/s0166- 4328(00) 00143-1 instname:Universidad Antonio Nariño reponame:Repositorio Institucional UAN repourl:https://repositorio.uan.edu.co/ spa Acceso abierto Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 application/pdf application/pdf application/pdf Universidad Antonio Nariño Doctorado en Ciencias de la salud Facultad de Medicina Bogotá - Circunvalar |
| spellingShingle | Pez Cebra Cafeina Etanol Estrés Zebra fish Caffein Ethanol Stress Franco Restrepo, Juan Esteban Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title | Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title_full | Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title_fullStr | Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title_full_unstemmed | Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title_short | Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra |
| title_sort | efectos comportamentales y moleculares del estres agudo etanol y la cafeina en el pez cebra |
| topic | Pez Cebra Cafeina Etanol Estrés Zebra fish Caffein Ethanol Stress |
| url | http://repositorio.uan.edu.co/handle/123456789/5090 |
| work_keys_str_mv | AT francorestrepojuanesteban efectoscomportamentalesymolecularesdelestresagudoetanolylacafeinaenelpezcebra |
