Uso de biomarcadores en el cáncer de cavidad oral
Cancer is the result of the uncontrolled proliferation of abnormal cells, either caused by genetic (molecular) changes that are transmitted from the parents to their children (hereditary) or that occur in the body throughout the life of a person (acquired). Each type of cancer has a unique group of...
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| Autores principales: | , , |
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| Otros Autores: | |
| Formato: | Trabajo de grado (Pregrado y/o Especialización) |
| Lenguaje: | spa |
| Publicado: |
Universidad Antonio Nariño
2021
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| Materias: | |
| Acceso en línea: | http://repositorio.uan.edu.co/handle/123456789/5046 |
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| Sumario: | Cancer is the result of the uncontrolled proliferation of abnormal cells,
either caused by genetic (molecular) changes that are transmitted from the
parents to their children (hereditary) or that occur in the body throughout the
life of a person (acquired). Each type of cancer has a unique group of
molecular changes in cancer cells. Technological advances have
made molecular testing possible, allowing clinicians to identify
the molecular differences between cancer cells and healthy cells.
The development of this work aims to propose and develop a study
on a marker (or pool of markers) that allows a diagnosis
precise state of the pathology and if it is easily obtained through
minimally invasive methods, we would be facing an ideal marker that would contribute to
timely treatment promoting the quality of life of patients,
we will talk about microRNAs, which are small RNAs that regulate the expression
of your target genes through decreased expression of proteins
encoded by these genes, by repression of translation and / or degradation
of its mRNA. MiRNAs play a fundamental role in virtually all
cellular processes including development, function and survival. miRNAs are
as critical regulators of immune tolerance and autoimmunity,
These are as potential new therapeutic targets for the treatment of
multiple diseases. |
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