Estudio del papel de la Laminina Beta 1 en células endoteliales de la barrera hematoencefálica (hCMEC/D3) bajo condiciones inflamatorias

The blood-brain barrier is crucial for protecting the central nervous system, and its dysfunction is associated with various neurological diseases. The present study investigates the role of laminin beta 1 in blood-brain barrier integrity and its influence on cell viability using a model of human mi...

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Bibliographic Details
Main Authors:	González Bonilla, Emily Vanessa, Losada Barragán, Mónica, Vargas Sánchez, Karina
Other Authors:	Losada Barragán , Mónica
Format:	Tesis/Trabajo de grado - Monografía - Pregrado
Language:	Español
Published:	Universidad Antonio Nariño 2025
Subjects:	Barrera hematoencefálica Uniones estrechas Matriz extracelular Inflamación Laminina blood-brain barrier tight junctions extracellular matrix inflammation laminin
Online Access:	https://repositorio.uan.edu.co/handle/123456789/12193
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Summary:	The blood-brain barrier is crucial for protecting the central nervous system, and its dysfunction is associated with various neurological diseases. The present study investigates the role of laminin beta 1 in blood-brain barrier integrity and its influence on cell viability using a model of human microvascular endothelial cells exposed to interleukin 1 beta-induced inflammation.