Deterioro Cognitivo tras Administracion de Dosis Subumbrales de Pilocarpina
INTRODUCTION: The present study sought to determine if there is deterioration cognitive function in Wistar rats to which a single subthreshold dose of pilocarpine and that were evaluated using an object recognition test. MATERIAL AND METHODS: Wistar rats (255±34 g) obtained from the National Institu...
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| Other Authors: | |
| Format: | Tesis/Trabajo de grado - Monografía - Pregrado |
| Language: | Español |
| Published: |
Universidad Antonio Nariño
2024
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| Subjects: | |
| Online Access: | https://repositorio.uan.edu.co/handle/123456789/11680 |
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| Summary: | INTRODUCTION: The present study sought to determine if there is deterioration
cognitive function in Wistar rats to which a single subthreshold dose of
pilocarpine and that were evaluated using an object recognition test.
MATERIAL AND METHODS: Wistar rats (255±34 g) obtained from the National Institute of
Health and kept in the stable in pairs at a constant temperature (24º±1)
with water and food ad libitum, they were divided into two experimental groups; Group A
(control) to which a single dose of physiological solution was injected (0.9% in 0.5 ml,
i.p) and Group B (experimental) to which a single subthreshold dose of
pilocarpine (200 mg/kg in 0.5 ml, i.p) long-term memory was evaluated by test
object recognition. |
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