Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease
Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early...
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UNIVERSIDAD ANTONIO NARIÑO
2016
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| Online Access: | https://revistas.uan.edu.co/index.php/ingeuan/article/view/408 https://repositorio.uan.edu.co/handle/123456789/10471 |
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| author | Suárez-Revelo, Jazmín X. |
| author_facet | Suárez-Revelo, Jazmín X. |
| author_sort | Suárez-Revelo, Jazmín X. |
| collection | DSpace |
| description | Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early preclinical changes related to Alzheimer's disease. The Event Related Potentials are a powerful tool used for the study of the neural substrates of cognitive function and deterioration. The connectivity analysis emerges as an alternative to the average approach typical in Event Related Potentials. In the current work two groups, mutation carriers and non-carriers, perform a memory task during Electroencephalography recording. Brain graphs are built at different time points using the directed Direct Transfer Function. Our results show how the dynamical study of the connectivity might help to detect neuronal changes in preclinical stage of Alzheimer's disease. |
| format | info:eu-repo/semantics/article |
| id | repositorio.uan.edu.co-123456789-10471 |
| institution | Repositorio Digital UAN |
| language | spa |
| publishDate | 2016 |
| publisher | UNIVERSIDAD ANTONIO NARIÑO |
| record_format | dspace |
| spelling | repositorio.uan.edu.co-123456789-104712024-10-14T03:49:04Z Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease Suárez-Revelo, Jazmín X. Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early preclinical changes related to Alzheimer's disease. The Event Related Potentials are a powerful tool used for the study of the neural substrates of cognitive function and deterioration. The connectivity analysis emerges as an alternative to the average approach typical in Event Related Potentials. In the current work two groups, mutation carriers and non-carriers, perform a memory task during Electroencephalography recording. Brain graphs are built at different time points using the directed Direct Transfer Function. Our results show how the dynamical study of the connectivity might help to detect neuronal changes in preclinical stage of Alzheimer's disease. 2016-02-24 2024-10-10T02:25:33Z 2024-10-10T02:25:33Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/version/c_970fb48d4fbd8a85 https://revistas.uan.edu.co/index.php/ingeuan/article/view/408 https://repositorio.uan.edu.co/handle/123456789/10471 spa https://revistas.uan.edu.co/index.php/ingeuan/article/view/408/343 https://creativecommons.org/licenses/by-nc-sa/4.0 http://purl.org/coar/access_right/c_abf2 application/pdf UNIVERSIDAD ANTONIO NARIÑO INGE@UAN - TENDENCIAS EN LA INGENIERÍA; Vol. 6 Núm. 11 (2015) 2346-1446 2145-0935 |
| spellingShingle | Suárez-Revelo, Jazmín X. Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_full | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_fullStr | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_full_unstemmed | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_short | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_sort | dynamical brain connectivity markers in presymptomatic alzheimer s disease |
| url | https://revistas.uan.edu.co/index.php/ingeuan/article/view/408 https://repositorio.uan.edu.co/handle/123456789/10471 |
| work_keys_str_mv | AT suarezrevelojazminx dynamicalbrainconnectivitymarkersinpresymptomaticalzheimersdisease |
