Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano
The development of new methods and/or devices for the diagnosis of diseases, toxic agents, contaminants, and other analytes of environmental, clinical, and biotechnological interest has been the subject of extensive studies. These studies prioritize the various interactions that can occur between th...
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UNIVERSIDAD ANTONIO NARIÑO
2023
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| Online Access: | https://revistas.uan.edu.co/index.php/saywa/article/view/1590 |
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| author | García Contreras, Germán Antonio |
| author_facet | García Contreras, Germán Antonio |
| author_sort | García Contreras, Germán Antonio |
| collection | OJS |
| description | The development of new methods and/or devices for the diagnosis of diseases, toxic agents, contaminants, and other analytes of environmental, clinical, and biotechnological interest has been the subject of extensive studies. These studies prioritize the various interactions that can occur between the analyte and the molecule responsible for recognition, also known as the bioreceptor. This review presents some strategies that have been developed over the past 20 years for the early detection of human papillomavirus (HPV) infection.
Currently, HPV is one of the most common sexually transmitted infections. While the majority of infections are transient and do not cause diseases, some infections can persist and lead to cervical cancer. The most widely used bioreceptors for designing new diagnostic methods are typically synthetic peptides derived from the L1 proteins of the human papillomavirus. The development of an efficient, cost-effective, sensitive, and specific bioreceptor for antibodies generated by HPV is crucial for the advancement of these new diagnostic tools. |
| format | Digital |
| id | revistas.uan.edu.co-article-1590 |
| institution | Revista SAYWA |
| language | spa |
| publishDate | 2023 |
| publisher | UNIVERSIDAD ANTONIO NARIÑO |
| record_format | ojs |
| spelling | revistas.uan.edu.co-article-15902023-07-24T17:38:29Z Synthetic peptides in the development of alternative methods of diagnosis and control of human papillomavirus Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano García Contreras, Germán Antonio diagnóstico cáncer de cuello uterino SPSS HPV bioreceptor HPV bioreceptor diagnosis SPSS cervical cancer The development of new methods and/or devices for the diagnosis of diseases, toxic agents, contaminants, and other analytes of environmental, clinical, and biotechnological interest has been the subject of extensive studies. These studies prioritize the various interactions that can occur between the analyte and the molecule responsible for recognition, also known as the bioreceptor. This review presents some strategies that have been developed over the past 20 years for the early detection of human papillomavirus (HPV) infection. Currently, HPV is one of the most common sexually transmitted infections. While the majority of infections are transient and do not cause diseases, some infections can persist and lead to cervical cancer. The most widely used bioreceptors for designing new diagnostic methods are typically synthetic peptides derived from the L1 proteins of the human papillomavirus. The development of an efficient, cost-effective, sensitive, and specific bioreceptor for antibodies generated by HPV is crucial for the advancement of these new diagnostic tools. El desarrollo de nuevos métodos y/o dispositivos para el diagnóstico de enfermedades, agentes tóxicos, contaminantes, entre otros analitos de interés ambiental, clínico y biotecnológico ha sido tema de amplios estudios que priorizan entre las diferentes interacciones que se pueden dar entre el analito y la molécula encargada del reconocimiento también conocido como bioreceptor. En esta revisión se presentan algunas estrategias se han venido desarrollando durante los últimos 20 años para la detección temprana de la infección del virus del papiloma humano. Actualmente el VPH es una de las infecciones de transmisión sexual más comunes, si bien la mayoría de las infecciones son transitorias y no causan enfermedades, algunas infecciones pueden persistir y producir cáncer de cuello uterino. Los bioreceptores más ampliamente utilizados para el diseño de nuevos métodos de diagnóstico generalmente son péptidos sintéticos derivados de las proteínas L1 del virus del papiloma humano. El desarrollo de un bioreceptor eficiente, económico, sensible y específico para anticuerpos generados por el VPH es fundamental para el desarrollo de estas nuevas herramientas de diagnóstico. UNIVERSIDAD ANTONIO NARIÑO 2023-06-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Divulgación científica application/pdf https://revistas.uan.edu.co/index.php/saywa/article/view/1590 10.54104/saywa.v4n5.1590 REVISTA SAYWA; Vol. 4 Núm. 5 (2022); 47-56 2744-8576 2711-1571 10.54104/saywa.v4n5 spa https://revistas.uan.edu.co/index.php/saywa/article/view/1590/1193 Derechos de autor 2022 Germán Antonio García Contreras https://creativecommons.org/licenses/by-nc-sa/4.0 |
| spellingShingle | diagnóstico cáncer de cuello uterino SPSS HPV bioreceptor HPV bioreceptor diagnosis SPSS cervical cancer García Contreras, Germán Antonio Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title | Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title_alt | Synthetic peptides in the development of alternative methods of diagnosis and control of human papillomavirus |
| title_full | Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title_fullStr | Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title_full_unstemmed | Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title_short | Péptidos sintéticos en el desarrollo de métodos alternativos de diagnóstico y control de virus del papiloma humano |
| title_sort | peptidos sinteticos en el desarrollo de metodos alternativos de diagnostico y control de virus del papiloma humano |
| topic | diagnóstico cáncer de cuello uterino SPSS HPV bioreceptor HPV bioreceptor diagnosis SPSS cervical cancer |
| topic_facet | diagnóstico cáncer de cuello uterino SPSS HPV bioreceptor HPV bioreceptor diagnosis SPSS cervical cancer |
| url | https://revistas.uan.edu.co/index.php/saywa/article/view/1590 |
| work_keys_str_mv | AT garciacontrerasgermanantonio syntheticpeptidesinthedevelopmentofalternativemethodsofdiagnosisandcontrolofhumanpapillomavirus AT garciacontrerasgermanantonio peptidossinteticoseneldesarrollodemetodosalternativosdediagnosticoycontroldevirusdelpapilomahumano |
