Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino
Propolis is produced by honeybees from the resins and balsams of plants and characterized by its complex chemical composition. Bees use propolis to protect the hive, to seal holes and to avoid infectious diseases that may affect bee health. Humans have used propolis for medicinal purposes since anci...
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| Format: | Tesis y disertaciones (Maestría y/o Doctorado) |
| Language: | spa |
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Universidad Antonio Nariño
2023
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| Online Access: | http://repositorio.uan.edu.co/handle/123456789/8027 |
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| author | Pardo Mora, Dolly Patricia |
| author2 | Torres García, Orlando |
| author_facet | Torres García, Orlando Pardo Mora, Dolly Patricia |
| author_sort | Pardo Mora, Dolly Patricia |
| collection | DSpace |
| description | Propolis is produced by honeybees from the resins and balsams of plants and
characterized by its complex chemical composition. Bees use propolis to protect the hive,
to seal holes and to avoid infectious diseases that may affect bee health. Humans have
used propolis for medicinal purposes since ancient times, and its effectiveness as an
antimicrobial, immunomodulatory, antiparasitic, and antitumor agent has been
demonstrated recently. |
| format | Tesis y disertaciones (Maestría y/o Doctorado) |
| id | repositorio.uan.edu.co-123456789-8027 |
| institution | Repositorio Digital UAN |
| language | spa |
| publishDate | 2023 |
| publisher | Universidad Antonio Nariño |
| record_format | dspace |
| spelling | repositorio.uan.edu.co-123456789-80272024-10-09T22:43:02Z Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino Pardo Mora, Dolly Patricia Torres García, Orlando Sforcin, Jose Mauricio Gutiérrez, Rafael María Propóleo Osteosarcoma Apoptosis Expresión génica. 14.18 P226p Propolis Osteosarcoma Apoptosis Gene Expression Propolis is produced by honeybees from the resins and balsams of plants and characterized by its complex chemical composition. Bees use propolis to protect the hive, to seal holes and to avoid infectious diseases that may affect bee health. Humans have used propolis for medicinal purposes since ancient times, and its effectiveness as an antimicrobial, immunomodulatory, antiparasitic, and antitumor agent has been demonstrated recently. El propóleo es un material producido por las abejas a partir de resinas y bálsamos de plantas, caracterizado por su compleja composición química. Las abejas lo utilizan como medio de protección, sellando espacios y adicionalmente para evitar procesos infecciosos que puedan afectar la salud de la colmena. El humano ha usado el propóleo desde tiempos ancestrales con fines medicinales y en la época moderna ha sido posible demostrar su efecto como antimicrobiano, inmunomodulador, antiparasitario y antitumoral, entre otros. Doctor(a) en Ciencia Aplicada Doctorado Presencial Monografía 2023-05-23T21:19:57Z 2023-05-23T21:19:57Z 2018-02-18 Tesis y disertaciones (Maestría y/o Doctorado) info:eu-repo/semantics/acceptedVersion http://purl.org/coar/resource_type/c_bdcc http://purl.org/coar/version/c_970fb48d4fbd8a85 http://repositorio.uan.edu.co/handle/123456789/8027 Ahn, M. R., Kunimasa, K., Ohta, T., Kumazawa, S., Kamihira, M., Kaji, K., . . . Nakayama, T. (2007). Suppression of tumor-induced angiogenesis by Brazilian propolis: Major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Cancer Letters, 252(2), 235-243. doi:10.1016/j.canlet.2006.12.039 Al-Khan A., Gunn H.J., Day M.J., Tayebi M., Ryan S.D., Kuntz C.A., Saad E.S., Richardson S.J., Danks J.A. 2017. Immunohistochemical Validation of Spontaneously Arising Canine Osteosarcoma as a Model for Human Osteosarcoma. Journal of Comparative Pathology. Volume 157, Issue 4: 256-265 Alday, E., Valencia, D., Carreno, A. L., Picerno, P., Piccinelli, A. L., Rastrelli, L., . . . Velazquez, C. (2015). Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B-cell lymphoma cell line. Chemico-Biological Interactions, 242, 35-44. doi:10.1016/j.cbi.2015.09.013 Bankova, Castro, D., & Marcucci. (2000). Propolis: Recent advances in chemistry and plant origin. Apidologie, 31(1), 3-15. Bankova, V. (2005). Chemical diversity of propolis and the problem of standardization. Journal of Ethnopharmacology, 100(1–2), 114-117. doi:http://dx.doi.org/10.1016/j.jep.2005.05.004 Bankova, V., Popova, M., & Trusheva, B. (2016). NEW EMERGING FIELDS OF APPLICATION OF PROPOLIS. Macedonian Journal of Chemistry and Chemical Engineering, 35(1), 1-11. doi:10.20450/mjcce.2016.864 Bartolomeu, A. R., Frión-Herrera, Y., da Silva, L. M., Romagnoli, G. G., de Oliveira, D. E., & Sforcin, J. M. (2016). Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells. Biomedicine & Pharmacotherapy, 81, 48-55. doi:http://dx.doi.org/10.1016/j.biopha.2016.03.049 Bernardino, P.N., Bersano, P.R.O., Lima Neto, J.F., Sforcin, J.M. Positive effects of antitumor drugs in combination with propolis on canine osteosarcoma cells (spOS- 2) and mesenchymal stem cells. Biomedicine & Pharmacotherapy, in press. Bertram, J. S. (2000). The molecular biology of cancer. Molecular Aspects of Medicine, 21(6), 167-223. doi:http://dx.doi.org/10.1016/S0098-2997(00)00007-8 Bittencourt, M. L. F., Ribeiro, P. R., Franco, R. L. P., Hilhorst, H. W. M., de Castro, R. D., & Fernandez, L. G. (2015). Metabolite profiling, antioxidant and antibacterial activities of Brazilian propolis: Use of correlation and multivariate analyses to identify potential bioactive compounds. Food Research International, 76, 449-457. doi:10.1016/j.foodres.2015.07.008 instname:Universidad Antonio Nariño reponame:Repositorio Institucional UAN repourl:https://repositorio.uan.edu.co/ spa Acceso abierto Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 application/pdf application/pdf Universidad Antonio Nariño Doctorado en Ciencia Aplicada Doctorado en Ciencia Aplicada Bogotá - Circunvalar |
| spellingShingle | Propóleo Osteosarcoma Apoptosis Expresión génica. 14.18 P226p Propolis Osteosarcoma Apoptosis Gene Expression Pardo Mora, Dolly Patricia Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title | Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title_full | Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title_fullStr | Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title_full_unstemmed | Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title_short | Potencial antitumoral de propóleos colombianos: caracterización química y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| title_sort | potencial antitumoral de propoleos colombianos caracterizacion quimica y mecanismos involucrados en la citotoxicidad in vitro contra osteosarcoma canino |
| topic | Propóleo Osteosarcoma Apoptosis Expresión génica. 14.18 P226p Propolis Osteosarcoma Apoptosis Gene Expression |
| url | http://repositorio.uan.edu.co/handle/123456789/8027 |
| work_keys_str_mv | AT pardomoradollypatricia potencialantitumoraldepropoleoscolombianoscaracterizacionquimicaymecanismosinvolucradosenlacitotoxicidadinvitrocontraosteosarcomacanino |
