Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2
The World Health Organization declared the infection named COVID-19 as a Public Health Emergency of International Concern on January 30, 2020, caused by the RNA virus called Coronavirus, causing more than 800 thousand deaths worldwide.(1) According to research carried out by Piera Valenti, they desc...
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Universidad Antonio Nariño
2022
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| author | Cerquera Muñoz, Carmen Alicia Urrutia Rivas, Yaney Yuliana Bryan Lopera, Crishnaisha Arias Vivas, Flor María |
| author2 | Garzón Parra, Johanna |
| author_facet | Garzón Parra, Johanna Cerquera Muñoz, Carmen Alicia Urrutia Rivas, Yaney Yuliana Bryan Lopera, Crishnaisha Arias Vivas, Flor María |
| author_sort | Cerquera Muñoz, Carmen Alicia |
| collection | DSpace |
| description | The World Health Organization declared the infection named COVID-19 as a Public Health Emergency of International Concern on January 30, 2020, caused by the RNA virus called Coronavirus, causing more than 800 thousand deaths worldwide.(1) According to research carried out by Piera Valenti, they describe: “Coronavirus belongs to the Coronaviridae family, specifically of the Delta genus. coronavirus and its name is SARS-CoV-2” (2); This virus is similar to the SARS-CoV at the nucleotide level, and possesses a sense single-stranded RNA genome positive with predisposition to epithelial cells and the respiratory system; this virus contains an encapsulated form that has a spike glycoprotein interacting with the receptor binding domain. The purpose of this bibliographical study is to understand and analyze that the virus does not It only affects the heart, lungs, kidneys, liver, digestive tract, and liver. blood vessels, but there is also growing clinical and scientific evidence of that the human ocular surface may represent an additional route of entry. In the evidence has shown that some respiratory viruses, including SARS CoV cause eye complications such as conjunctivitis in infected people and in they do establish a respiratory infection after ocular exposure. |
| format | Trabajo de grado (Pregrado y/o Especialización) |
| id | repositorio.uan.edu.co-123456789-6542 |
| institution | Repositorio Digital UAN |
| language | spa |
| publishDate | 2022 |
| publisher | Universidad Antonio Nariño |
| record_format | dspace |
| spelling | repositorio.uan.edu.co-123456789-65422024-10-09T23:35:32Z Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 Cerquera Muñoz, Carmen Alicia Urrutia Rivas, Yaney Yuliana Bryan Lopera, Crishnaisha Arias Vivas, Flor María Garzón Parra, Johanna Hernández, César Augusto SARS-CoV-2 Receptores ACE2 Proteasa TMPRSS2 Susceptibilidad Patologías oculares 617.7 SARS-CoV-2 ACE2 receptors TMPRSS2 protease Susceptibility Ocular pathologies The World Health Organization declared the infection named COVID-19 as a Public Health Emergency of International Concern on January 30, 2020, caused by the RNA virus called Coronavirus, causing more than 800 thousand deaths worldwide.(1) According to research carried out by Piera Valenti, they describe: “Coronavirus belongs to the Coronaviridae family, specifically of the Delta genus. coronavirus and its name is SARS-CoV-2” (2); This virus is similar to the SARS-CoV at the nucleotide level, and possesses a sense single-stranded RNA genome positive with predisposition to epithelial cells and the respiratory system; this virus contains an encapsulated form that has a spike glycoprotein interacting with the receptor binding domain. The purpose of this bibliographical study is to understand and analyze that the virus does not It only affects the heart, lungs, kidneys, liver, digestive tract, and liver. blood vessels, but there is also growing clinical and scientific evidence of that the human ocular surface may represent an additional route of entry. In the evidence has shown that some respiratory viruses, including SARS CoV cause eye complications such as conjunctivitis in infected people and in they do establish a respiratory infection after ocular exposure. La Organización mundial de la Salud declaró la infección denominada COVID-19 como una emergencia de salud pública de preocupación internacional el 30 de enero de 2020, causada por el virus ARN denominado Coronavirus, causante de más de 800 mil muertes a nivel mundial.(1) Según investigaciones realizadas por Piera Valenti describe: “Coronavirus pertenece a la familia Coronaviridae, específicamente del género Delta coronavirus y su denominación es SARS-CoV-2” (2); este virus presenta similitud con el SARS-CoV a nivel de nucleótidos, y posee un genoma de ARN monocatenario de sentido positivo con predisposición a las células epiteliales y al sistema respiratorio; éste virus contiene una forma encapsulada que tiene una glicoproteína espiga interactuando con el dominio de unión al receptor. La finalidad de este estudio bibliográfico es comprender y analizar que el virus no solamente afecta al corazón, al pulmón, los riñones, el hígado, el tracto digestivo y los vasos sanguíneos, sino que también existe una creciente evidencia clínica y científica de que la superficie ocular humana puede representar una ruta adicional de entrada. En las evidencias se ha demostrado que algunos virus respiratorios por lo que se incluye el SARS CoV provocan complicaciones oculares como la conjuntivitis en personas infectadas y en sí establecen una infección respiratoria tras la exposición ocular. Optómetra Pregrado Presencial Monografía 2022-05-14T14:20:03Z 2022-05-14T14:20:03Z 2021-11-11 Trabajo de grado (Pregrado y/o Especialización) info:eu-repo/semantics/acceptedVersion http://purl.org/coar/resource_type/c_7a1f http://purl.org/coar/version/c_970fb48d4fbd8a85 http://repositorio.uan.edu.co/handle/123456789/6542 Zhang C, Chen Y, Li L, Yang Y, He J, Chen C, et al. Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2. Mol Biomed [Internet]. 2020 Dec 20 [cited 2020 Aug 27]; 1(1):5. Available from: http://link.springer.com/10.1186/s43556-020-00005-0 Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, et al. Coexpression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. Ocul Surf. 2020 Jun 3; Al-Qahtani AA. Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2): Emergence, history, basic and clinical aspects. Saudi Journal of Biological Sciences. Elsevier B.V.; 2020. Lan J, Ge J, Yu J, Shan S, Zhou H, Fan S, et al. Structure of the SARS-CoV2 spike receptor-binding domain bound to the ACE2 receptor. Nature [Internet]. 2020 May 14 [cited 2020 Sep 16]; 581(7807):215–20. Available from: https://doi.org/10.1038/s41586-020-2180-5 Coronavirus (CoV) GLOBAL [Internet]. [cited 2020 Oct 20]. Available from: https://www.who.int/es/health-topics/coronavirus Zhang C, Chen Y, Li L, Yang Y, He J, Chen C, et al. Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2. Mol Biomed [Internet]. 2020 Dec 20 [cited 2020 Aug 27]; 1(1):5. Available from: http://link.springer.com/10.1186/s43556-020-00005-0 Machhi J, Herskovitz J, Senan AM, Dutta D, Nath B, Oleynikov MD, et al. The Natural History, Pathobiology, and Clinical Manifestations of SARSCoV-2 Infections [Internet]. Journal of Neuroimmune Pharmacology. Springer; 2020 [cited 2020 Aug 28]. p. 1. Available from: /pmc/articles/PMC7373339/?report=abstract Liu Z, Zheng H, Lin H, Li M, Yuan R, Peng J, et al. Identification of common deletions in the spike protein of SARS-CoV-2. J Virol [Internet]. 2020 Jun 22 [cited 2020 Aug 27]; 94(17):790–810. Available from: /pmc/articles/PMC7431800/? Report=abstract. Da Silva PG, Mesquita JR, de São José Nascimento M, Ferreira VAM. Viral, host and environmental factors that favor anthropozoonotic spillover of coronaviruses: An opinionated review, focusing on SARS-CoV, MERS-CoV and SARS-CoV-2. Sci Total Environ. 2020 Aug 1; 750:141483. Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, et al. Coexpression of SARS-CoV-2 entry genes in the superficial adult humanconjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. Ocul Surf. 2020 Jun 3; Campione E, Cosio T, Rosa L, Lanna C, Girolamo S Di, Gaziano R, et al instname:Universidad Antonio Nariño reponame:Repositorio Institucional UAN repourl:https://repositorio.uan.edu.co/ spa Acceso a solo metadatos Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/closedAccess http://purl.org/coar/access_right/c_14cb application/pdf application/pdf application/pdf Universidad Antonio Nariño Optometría Facultad de Optometría Medellín |
| spellingShingle | SARS-CoV-2 Receptores ACE2 Proteasa TMPRSS2 Susceptibilidad Patologías oculares 617.7 SARS-CoV-2 ACE2 receptors TMPRSS2 protease Susceptibility Ocular pathologies Cerquera Muñoz, Carmen Alicia Urrutia Rivas, Yaney Yuliana Bryan Lopera, Crishnaisha Arias Vivas, Flor María Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title | Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title_full | Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title_fullStr | Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title_full_unstemmed | Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title_short | Receptores ACE-2 en superficie ocular y susceptibilidad con SARS CoV-2 |
| title_sort | receptores ace 2 en superficie ocular y susceptibilidad con sars cov 2 |
| topic | SARS-CoV-2 Receptores ACE2 Proteasa TMPRSS2 Susceptibilidad Patologías oculares 617.7 SARS-CoV-2 ACE2 receptors TMPRSS2 protease Susceptibility Ocular pathologies |
| url | http://repositorio.uan.edu.co/handle/123456789/6542 |
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