Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease
Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early...
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | info:eu-repo/semantics/publishedVersion |
| Lenguaje: | spa |
| Publicado: |
Universidad Antonio Nariño
2021
|
| Acceso en línea: | http://revistas.uan.edu.co/index.php/ingeuan/article/view/408 http://repositorio.uan.edu.co/handle/123456789/3966 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1812648107685445632 |
|---|---|
| author | Suárez-Revelo, Jazmín X. |
| author_facet | Suárez-Revelo, Jazmín X. |
| author_sort | Suárez-Revelo, Jazmín X. |
| collection | DSpace |
| description | Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early preclinical changes related to Alzheimer's disease. The Event Related Potentials are a powerful tool used for the study of the neural substrates of cognitive function and deterioration. The connectivity analysis emerges as an alternative to the average approach typical in Event Related Potentials. In the current work two groups, mutation carriers and non-carriers, perform a memory task during Electroencephalography recording. Brain graphs are built at different time points using the directed Direct Transfer Function. Our results show how the dynamical study of the connectivity might help to detect neuronal changes in preclinical stage of Alzheimer's disease. |
| format | info:eu-repo/semantics/publishedVersion |
| id | repositorio.uan.edu.co-123456789-3966 |
| institution | Repositorio Digital UAN |
| language | spa |
| publishDate | 2021 |
| publisher | Universidad Antonio Nariño |
| record_format | dspace |
| spelling | repositorio.uan.edu.co-123456789-39662024-10-09T23:11:43Z Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease Suárez-Revelo, Jazmín X. Alzheimer's disease is the most prevalent cause of dementia generally with an onset after the 65 years. However, there are some genetic mutations that induce the onset of the neurocognitive symptoms before that age. The study of mutation carriers provides a unique opportunity to identify early preclinical changes related to Alzheimer's disease. The Event Related Potentials are a powerful tool used for the study of the neural substrates of cognitive function and deterioration. The connectivity analysis emerges as an alternative to the average approach typical in Event Related Potentials. In the current work two groups, mutation carriers and non-carriers, perform a memory task during Electroencephalography recording. Brain graphs are built at different time points using the directed Direct Transfer Function. Our results show how the dynamical study of the connectivity might help to detect neuronal changes in preclinical stage of Alzheimer's disease. 2021-06-16T13:53:17Z 2021-06-16T13:53:17Z 2016-02-24 info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/article http://purl.org/coar/version/c_970fb48d4fbd8a85 http://revistas.uan.edu.co/index.php/ingeuan/article/view/408 http://repositorio.uan.edu.co/handle/123456789/3966 spa http://revistas.uan.edu.co/index.php/ingeuan/article/view/408/343 Acceso abierto Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 application/pdf Universidad Antonio Nariño 2346-1446 2145-0935 INGE@UAN - TENDENCIAS EN LA INGENIERÍA; Vol. 6 Núm. 11 (2015) |
| spellingShingle | Suárez-Revelo, Jazmín X. Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_full | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_fullStr | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_full_unstemmed | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_short | Dynamical brain connectivity markers in presymptomatic Alzheimer’s disease |
| title_sort | dynamical brain connectivity markers in presymptomatic alzheimer s disease |
| url | http://revistas.uan.edu.co/index.php/ingeuan/article/view/408 http://repositorio.uan.edu.co/handle/123456789/3966 |
| work_keys_str_mv | AT suarezrevelojazminx dynamicalbrainconnectivitymarkersinpresymptomaticalzheimersdisease |
